This web server is based RNA-MoIP, developed in the lab of Jérôme Waldispühl. See article Reinharz, V., Major, F., Waldispühl, J. Towards 3D structure prediction of large RNA molecules: an integer programming framework to insert local 3D motifs in RNA secondary structure. Bioinformatics 28(12): i207-14 (2012).
RNA-MoIP is an integer programming framework that refines predicted secondary structures (i.e. removes incorrect canonical base-pairs) to accommodate the insertion of RNA 3D motifs (i.e. hairpins, internal loops and k-way junctions). The predictions can be used as templates to generate complete 3D structures with the MC-Sym program.
RNA-MoIP download link: RNA-MoIP Webpage
- Vladimir Reinharz, François Major, and Jérôme Waldispühl. Towards 3D structure prediction of large RNA molecules: an integer programming framework to insert local 3D motifs in RNA secondary structure. Bioinformatics (Proceedings of ISMB 2012; Also appear in Conference Section), 28(12):i207-14, June 2012.
- Jérôme Waldispühl and Vladimir Reinharz. Modeling and predicting rna three-dimensional structures. Methods Mol Biol, 1269:101-21, 2015.
The web server was developed by Jason Yao et al. in Dr. Jérôme Waldispühl's lab at McGill University, Montreal, QC. For all relevant issues and suggestions please contact Jérôme Waldispühl: firstname.lastname@example.org